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that's, stimulation of CD74 with exogenous MIF could produce an too much inflammatory condition, as MIF is effective at stimulating CXCR2 and CXCR4 receptors in addition to CD74. CXCR2 and CXCR4 receptors when activated advertise influx of neutrophils and lymphocytes, respectively (63, sixty four). In healthier blood MIF is predominantly expressed
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